Malignant Pleural Effusion, an Unusual Presentation of Metastatic Adenoid Cystic Carcinoma: A Case Report and Review of the Literature 【Abstract】

[N A J Med Sci. 2017;10(1):8-12.   DOI:  10.7156/najms.2017.1001008]

Ayesha Arshad, MD

Adenoid cystic carcinoma (ACC) is an uncommon malignant neoplasm of the major and minor salivary glands that is known to have a long clinical course, behaving in an insidious and indolent fashion with multiple recurrences preceding distant metastasis. Reported here is a case of a patient presenting with shortness of breath and recurrent pleural effusion. Exfoliated ACC cells were observed on cytological evaluation, a rare occurrence. Mediastinal lymph node involvement was also confirmed on cytology. A primary site of origin was not found. In summary ACC can present in various body sites and pathologists should consider ACC in the differential diagnosis of a basaloid carcinoma of uncertain origin.

Key Words: adenoid cystic carcinoma, pleural effusion, metastatic tumor

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Ayesha Arshad, MD
Veteran Affairs Medical Center, Buffalo, NY and Department of Pathology, SUNY, Buffalo, NY

*Corresponding Author: Veteran Affairs Medical Center, Buffalo, NY and Department of Pathology, SUNY, Buffalo, NY. Tel: 716-862-8702. (Email: ayesha.arshad@va.gov)

CONFLICT OF INTEREST
The author has no conflict of interest to disclose.

ACKNOWLEDGEMENT
The author would like to acknowledge the effort and expertise provided by Christopher D’Angelis MD in painstakingly reviewing and editing the case report.

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