A Rare Case of Myelodysplastic Syndrome with Ring Sideroblasts, SF3B1 and TET2 Mutations in a Patient with Beta Thalassemia Trait

[N A J Med Sci. 2017;10(1):31-34.   DOI:  10.7156/najms.2017.1001031] Jeffrey Ahlstedt, MD; Yanhua Wang, MD, PhD; Yanan Fang, MD, PhD Concurrent myelodysplastic syndrome (MDS) and β-thalassemia trait is rare. We reported a case of a 59-year-old man with a known history… Continue Reading

ZAP70 Related Severe Combined Immunodeficiency Initially Diagnosed as Incomplete (Atypical) Kawasaki Disease

[N A J Med Sci. 2017;10(1):28-30.   DOI:  10.7156/najms.20171001028] Andrew Alexander, MD; Monika Pilichowska, MD ZAP70-related severe combined immunodeficiency (SCID) is a defect of the immune system characterized by absent or extremely low CD8+ T-cells and abnormal T-cell receptor signaling. This… Continue Reading

A Case of CD5-/Cyclin D1+/SOX11- Mantle Cell Lymphoma with an Aberrant Immunophenotype and Indolent Clinical Course

[N A J Med Sci. 2017;10(1):39-43.   DOI:  10.7156/najms.2017.1001039] Lei Zhang, MD, PhD; Nan Zhang, MD, PhD Mantle cell lymphoma (MCL) is a clinically aggressive B-cell lymphoma associated with 11q13 translocation, which leads to cyclin D1 overexpression in almost all cases.… Continue Reading

Small Bowel Ischemic Necrosis Secondary to Idiopathic Intimal and Medial Hyperplasia of Mesenteric Vessels: A Case Report

[N A J Med Sci. 2017;10(1):24-27.   DOI:  10.7156/najms.2017.1001024] Meenal Sharma, MD; Zhongren Zhou, MD, PhD* Small bowel ischemic necrosis secondary to idiopathic intimal and medial hyperplasia of mesenteric small vessels is rare. The mesenteric vascular diseases were recently classified as… Continue Reading

Polyostotic Fibrous Dysplasia Mimicking Metastatic Disease Radiographically: A Case Report and Literature Review

[N A J Med Sci. 2017;10(1):20-23.   DOI:  10.7156/najms.2017.1001020] David Gay, MD; Joey Philip, MD; Shahida Ahmed, MD; Jin Choe, MD; Donghong Cai, MD, PhD Fibrous dysplasia is a benign intramedullary lesion characterized by an excessive proliferation of cellular fibrous tissue… Continue Reading

Composite Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia/Small Cell Lymphoma with 17p Deletion: A Case Study

[N A J Med Sci. 2017;10(1):13-19.   DOI:  10.7156/najms.2017.1001013] Hanan Armanious, MD, PhD; Jean Deschênes, MD; Wei-Feng Dong, MD, PhD; Iyare Izevbaye, MD, PhD Here we describe a case of a composite mantle cell lymphoma (MCL) and chronic lymphocytic leukemia/small cell… Continue Reading

Malignant Pleural Effusion, an Unusual Presentation of Metastatic Adenoid Cystic Carcinoma: A Case Report and Review of the Literature

[N A J Med Sci. 2017;10(1):8-12.   DOI:  10.7156/najms.2017.1001008] Ayesha Arshad, MD Adenoid cystic carcinoma (ACC) is an uncommon malignant neoplasm of the major and minor salivary glands that is known to have a long clinical course, behaving in an insidious… Continue Reading

Evaluation of the Vysis IntelliFISH Hybridization Buffer and Vysis IntelliFISH Universal FFPE Pretreatment and Wash Kit in FISH Assays

[N A J Med Sci. 2017;10(1):5-7.   DOI:  10.7156/najms.2017.1001005] Jiawei Zhao, MS; Chengwen Li, BS; Jing Xiao, MS; Yingchun Zheng, MS; Kejing Tang, BS; Shenghua Chen, MD; Kun Ru, MD, PhD Standard fluorescence in-situ hybridization (FISH) technique requires a hybridization time… Continue Reading

The Prevalence of alpha-Thalassemia in Anemic US Veterans without Nutritional Deficiency or Abnormal Hemoglobin HPLC Pattern

[N A J Med Sci. 2017;10(1):1-4.   DOI:  10.7156/najms.2017.1001001] Jessenia Guerrero, MD; Oliver Cai; Shahida Ahmed, MD; Donghong Cai, MD, PhD Alpha-thalassemia is one of the most common hemoglobin genetic abnormalities. The primary defect is the reduced or absent production of… Continue Reading